Our horizontal forming machine, called as “The Revolution of Ampoule Manufacture”. Even after a half century, technical improvements still continue on.

Ampoules are manufactured through thermal processing and forming of a straight material grass tube. Shiotani Glass was the first company in the country that developed a machine that would form and cut the horizontally arranged material glass tubes while heating them. Since then, we have been supplying high-quality products with manufacturing expertise piled up for many years.

The horizontal forming machine we developed in 1959 was called “The Revolution of Ampoule Manufacture”. Ampoule forming machines were not available in Japan back then, but we stuck to develop it on our own to make improved and consistent quality, as well as to realize mass production. We have been improving our manufacturing technologies, as a pioneer of mechanized ampoule manufacture, to supply high-quality ampoules since then.

Ampoule manufacture with established unique technology

In addition to support for various use cases and requests, we also offer special processes such as silicoating and sulfur treatment.

For quality improvement common to all products

RO purified water cleaning and drying processes

Not limited to vials, the material glass tubes used for our pharmaceutical glass containers are subject to brush cleaning with RO purified water or shower cleaning before they are formed. After cleaning, the material tubes are dried and cooled in a batch mode by an electric drying oven to prevent from being contaminated. After that, they are kept under cover to keep cleanliness until immediately before forming.

Brush cleaning
Shower cleaning
Pure water system
Electric drying oven

Ampoule forming


Makes dents on and stretches material glass tube into the shape of ampoule and cuts it.

Size checker

Checks all sizes.

Mouth forming

Opens the tube end to form the mouth.

One point cut (OPC)

Adds color marking and one point cut.

Bottom forming

Melts and cuts the semifinished product equally in two, and forms the bottom.

Strain removal (Annealing)

Puts the vials into the annealing oven to remove strain.

Ampoule check

OPC check

Checks for proper mark and one point cut.

Appearance check 1

Visually checks for dirt or foreign material and proper mark shape.

Appearance check 2

Checks for mouth/bottom shapes and quantity.


Various case materials are supported.

Data spec

Material Borosilicate glass
Volume 1~20mL (White/Brown)
Image diagram
Standard specification (White) Unit:㎜
Volume A: Body diameter B: Total height C: Body perimeter D: Ball diameter E: Neck diameter F: Mouth diameter G: Seal diameter H: Body wall thickness
1mL 10.2 68.0 29.0 7.0 5.1 6.4 5.4 0.42
2mL 12.5 74.0 31.6 7.6 5.9 6.7 5.7 0.45
3mL 12.5 84.0 41.0 7.6 5.9 6.6 5.8 0.45
5mL 18.0 90.0 40.0 9.0 7.0 7.5 6.0 0.52
10mL 18.0 113.0 62.0 9.2 7.5 7.5 6.3 0.52
20mL 21.8 133.5 78.5 12.0 9.0 8.5 8.0 0.55

Non-standard sizes and volumes are also available. Contact us.

Special processes such as silicoating, sulfur treatment and silicone processing are supported.